Grooved Glaucoma Drainage Devices That Continuously Deliver Cyclosporine A Decrease Postsurgical Scar Formation in Rabbit Eyes
نویسندگان
چکیده
منابع مشابه
Glaucoma drainage devices; past, present, and future.
Glaucoma filtration surgery (GFS) has been shown to be more eVective at preventing disease progression than other primary treatment modalities in open angle glaucoma. 2 If it were possible to avoid complications associated with poor flow control, primary GFS would probably be offered more widely. Trabeculectomy, the procedure of choice in conventional GFS, has remained essentially unchanged for...
متن کاملThe Effect of Dry Eye Disease on Scar Formation in Rabbit Glaucoma Filtration Surgery
The success rate of glaucoma filtration surgery is closely related to conjunctival inflammation, and the main mechanism of dry eye disease (DED) is inflammation. The aim of this study was to evaluate the effect of DED on bleb scar formation after rabbit glaucoma filtration surgery. Sixteen New Zealand white rabbits were randomly divided into control and DED groups. A DED model was induced by tw...
متن کاملComparison of different biomaterials for glaucoma drainage devices.
OBJECTIVES To compare the inflammatory reaction associated with the insertion of silicone and polypropylene endplates and endplates made of a new biocompatible polymer, Vivathane, in the rabbit subconjunctival space. METHODS Similar-sized endplates made of 3 different biomaterials were sutured to the sclera in the superotemporal quadrant of the rabbit eye. Thirty eyes of 15 albino New Zealand...
متن کاملArtificial drainage devices for glaucoma surgery: an overview.
Artificial drainage devices (ADD) create an alternative pathway for aqueous drainage from the anterior chamber of an eye through a tube to the subconjunctival bleb connected to an equatorial plate under the conjunctiva. The ADDs, both valved and non-valved, are available for end stage or refractory glaucoma. Currently, some of these devices, particularly the Express shunt, are recommended for t...
متن کاملComparison of different biomaterials for glaucoma drainage devices: part 2.
BACKGROUND Inflammation associated with biomaterials may contribute to the failure of glaucoma drainage devices. OBJECTIVE To compare the inflammatory reaction associated with the insertion of Krupin silicone, Molteno polypropylene, and Acrosof end plates in the subconjunctival space of rabbits. METHODS Similar-sized glaucoma end plates made of 3 different biomaterials were sutured to the s...
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ژورنال
عنوان ژورنال: Investigative Opthalmology & Visual Science
سال: 2017
ISSN: 1552-5783
DOI: 10.1167/iovs.16-21065